General Information

  • ID:  hor004028
  • Uniprot ID:  A0A7M6UV78
  • Protein name:  Pyrokinin-2
  • Gene name:  100313507
  • Organism:  Nasonia vitripennis (Parasitic wasp)
  • Family:  Pyrokinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Nasonia (genus), Pteromalinae (subfamily), Pteromalidae (family), Chalcidoidea (superfamily), Parasitoida (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0005184 neuropeptide hormone activity
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  QETTFTPRL
  • Length:  9
  • Propeptide:  MELARLINGARTKAILCALLVIVLMANRVAGQYDGRGSDMVEGPRVERMHPETSGGCVGAHCLTQNSEGPVGAMWFGPRLGRRRRSDKFTPKKIEALSEMLGSPNWNLVTIPGGEDKRQETTFTPRLGRELENAISVYDLVRGLVSSVDDQNGKDRDQQAPPPMFPPRLGRTLLTPRLEHELRNLLRKLQMQ
  • Signal peptide:  MELARLINGARTKAILCALLVIVLMANRVAG
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A7M6UV78-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor004028_AF2.pdbhor004028_ESM.pdb

Physical Information

Mass: 123508 Formula: C48H77N13O16
Absent amino acids: ACDGHIKMNSVWY Common amino acids: T
pI: 6.41 Basic residues: 1
Polar residues: 3 Hydrophobic residues: 2
Hydrophobicity: -95.56 Boman Index: -2708
Half-Life: 0.8 hour Half-Life Yeast: 10 min
Half-Life E.Coli: >10 hour Aliphatic Index 43.33
Instability Index: 3562.22 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  20695486
  • Title:  Genomics and Peptidomics of Neuropeptides and Protein Hormones Present in the Parasitic Wasp Nasonia Vitripennis